Is Serious Game a vector of endogenous and exogenous economic development of the territory? What is the level of development of this emerging market? Does it bring structuring growth for businesses, citizens and the region? To the extent that the conditions are met in a territory, can we consider implementing a clustering strategy in the serious gaming sector? How do its nationals fit into territorial issues? How can we mobilize this economic fabric but also assets in Research & Development Innovation, in education and support systems to create a systemic and self-structuring dynamic?