In this paper we present a Digital Serious Game set in a medieval alchemical laboratory, aimed at disseminating the ancient knowledge of medicine distillation contained in the famous Adam Lonicer's Kreuterbuch (1569) treatise. The application is based on interactive Virtual Environments and available on multiple visualization technologies, ranging from simple touch-based tablet up to immersive environments such as CAVEs or Oculus Rift. The game comes as the latest development level of a larger international multidisciplinary project meant to explore novel methodologies to raise the awareness about ancient books, in particular the collection of the Gunnerus Library of Trondheim, with a special attention to the public of youngsters.
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