This article deals with Serious Game design methods. More specifically, it focuses on the following question: is there any universal series of “steps” to design a Serious Game? Or is the availability of several different design methods unavoidable? To try to answer this question, we will study a corpus of ten design methods suited to Serious Games. Most of these theoretical tools are coming from or aimed to industry professionals. This literary review will allow us to perform a comparative analysis over the various “steps” used by these methods, in order to identify a generic model for the design process of Serious Games.